 |
Case Report
Traumatic neuroma on the tongue tip: A case report and review of the literature
1 Department of Dental and Oral Surgery, Ogaki Tokushukai Hospital, 6-85, Hayashi-machi, Ogaki City, Gifu 503-0015, Japan
2 Department of Otolaryngology, Ogaki Tokushukai Hospital, 6-85, Hayashi-machi, Gifu 503-0015, Japan
3 Department of Diagnostic Pathology, Ogaki Tokushukai Hospital, 6-85-1, Hayashi-machi, Ogaki City, Gifu 503-0015, Japan
Address correspondence to:
Hideki Mori
Department of Diagnostic Pathology, Ogaki Tokushukai Hospital, 6-85-1, Hayashi-machi, Ogaki City, Gifu 503-0015,
Japan
Message to Corresponding Author
Article ID: 100045Z07YJ2024
Access full text article on other devices
Access PDF of article on other devices
How to cite this article
Jinno Y, Aoki M, Mori H. Traumatic neuroma on the tongue tip: A case report and review of the literature. J Case Rep Images Dent 2024;10(1):1–4.ABSTRACT
Introduction: Traumatic neuroma is a non-neoplastic proliferation of a nerve occurring in response to an injury or surgery. Traumatic neuroma on the tongue tip is a very rare proliferating lesion in the oral cavity. We present a case of traumatic neuroma on the tongue tip. This case may be valuable for understanding the pathogenesis of the neuroma.
Case Report: A 79-year-old man developed a painful nodule on the tongue tip. Histologically, the nodule consisted of a tortuous proliferation of nerve fascicles, and diagnosed as a traumatic neuroma. The bundles of the neuroma expressed a strong activity of the neural marker S-100. Expression of alpha smooth muscle actin (α-SMA) being a phenotypic marker of myoblast activity was also positive in the surrounding connective tissues of the nodule suggesting a relation to the painful natures of the neuroma. Cross-sectioned nerve bundles of the neuromas seemed to be 5–7 times larger than of the normal bundles suggesting intensity of proliferation the nerve bundles. The neuroma was considered to occur by repeated stimuli of the tongue tip to the front teeth.
Conclusion: Traumatic neuroma on the tongue tip is quite rare. Onset of the neuroma was suggested repeated stimuli of the tongue tip to the front teeth. Expression of α-SMA of the bundles of the neuroma seemed to accord with the painful natures of the neuroma.
Keywords: Pain, Tip, Tongue, Traumatic neuroma
SUPPORTING INFORMATION
Author Contributions:
Yosuke Jinno - Acquisition of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mitsuhiro Aoki - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Hideki Mori - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Yosuke Jinno et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
